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Cryogenic

Program


Wednesday September 7, 2011

10:00       Registration (coffee served on site)
12:30       Lunch available on campus
14:00       Introductory remarks

------        Overview and challenges                                                                                     

14:15       Jan Henrik Ardenkjaer-Larsen
       Dissolution-DNP polarizer for sterile use intent; considerations for clinical
       translational
14:45        Daniella Goldfarb
       Correlation of the EPR properties of perchlorotriphenylmethyl radicals and their
       efficiency as DNP polarizers

15:15       Coffee break

16:00       Thomas Prisner
       High field Dynamic Nuclear Polarization in Liquid
16:30       Miquel Pons
       Dissolution DNP and Quadrupolar Nuclei
16:45       Kevin Brindle
       Imaging metabolism - Watching tumours gasp and die with hyperpolarised MRI
17:15        Huiming Zhang
       Cancer Biology by Hyperpolarized 13C/15N MRSI: From Basic Discovery to Clinic
       Research

17:45       Free evening



Thursday September 8, 2011

------         Liquid state DNP techniques                                                                                

8:30         Christian Hilty
         Solid-to-liquid state DNP: Beyond the Small Molecule Limit
9:00         Philip Lottmann
         Shuttle DNP Spectrometer with a Two-Center Magnet
9:15         Jan van Bentum
         High field liquid state DNP in a microfluidic context
9:30         Sami Jannin
         Enhancing Polarization Lifetimes for Dissolution-DNP Experiments

10:00       Coffee break

10:45       Walter Koeckenberger
       Simulating Spin Dynamics During Dynamic Nuclear Polarization
11:15       John Franck
       Quantitative Overhauser Effect Dynamic Nuclear Polarization (OE-DNP) for the
       Measurement of Hydration Dynamics

11:30       Poster session

12:30       Lunch served on site

------        Instrumentation and design                                                                                  

14:00       Stefano Alberti
       THz-instrumentation development for gyrotron-DNP applications: from source to
       sample
14:30       Graham Smith
       Wideband High Power Pulse Techniques for EPR and DNP
15:00       Emile de Rijk
       THz-Waves Channeling in a Monolithic Saddle-Coil for DNP-NMR
15:15       Patrick Hautle
       DNP using photo-excited triplet states and its application to build a neutron spin
       filter

15:45       Coffee break

16:30       Melanie Rosay
       Solid-State DNP Spectrometer for Applications to Biological Solids and Material
       Science
17:00       Li Wang
       High deuteron Polarization in polymer target materials
17:15       Richard Temkin
       460 and 527 GHz Gyrotron Systems for DNP/NMR

19:15       Harbour of Ouchy: Conference dinner cruise on Lake Geneva
Dinner will be served on the most prestigious Swiss steam boat, La Suisse.

RLC


Friday September 9, 2011

------        Solid state DNP techniques I                                                                                 

8:30         Anne Lesage
         Dynamic nuclear polarization NMR spectroscopy for the characterization of
         material surfaces
9:00         Olivier Lafon
         Beyond the silica surface by direct 29Si dynamic nuclear polarization
9:15         Alexey Potapov
         Low temperature DNP for characterization of static samples using 2D-exchange
         experiments
9:30         Mark Smith
         A Novel Spectrometer Design for DNP Enhanced Solid State MAS NMR using a
         Quasioptical Microwave Transmission Design and Investigation of the Factors
         Determining the DNP Signal Enhancement at 94 GHz

10:00       Coffee break

10:30       Paul Tordo
       Properties of dinitroxides for use in Dynamic Nuclear Polarization
11:00       Albert Smith
       Solid Effect Dynamic Nuclear Polarization and Polarization Transfer Pathways
11:15       Yoh Matsuki
       Solid-State NMR Enhanced by Helium-Cooling and -Spinning Dynamic Nuclear
       Polarization at 14 T and 30 K

11:45       Poster session

12:45       Lunch served on site

------        Solid state DNP techniques II                                                                                

14:00       Marc Caporini
       Fractional Spin-Labeling of Polymers for Enhancing NMR Sensitivity by Dynamic
       Nuclear Polarization without Glass-forming Solvents
14:30       Ümit Akbey
       High-Field DNP Enhanced NMR Spectroscopy of Proteins in the Solid-State:
       Application to Deuterated and Protonated Proteins
14:45       Björn Corzilius
       High Field Dynamic Nuclear Polarization with High-Spin Transition Metal Ions

15:00       Coffee break

------        Biomedical applications I                                                                                     

15:45       Mathilde Lerche
       Yeast glycolysis through the magnifying glass of 13C-Hyperpolarization
16:15       Thomas Eykyn
       Studies of drug treatment response by 13C DNP MRS – correlations with
       mechanisms of action
16:30       Daniel Vigneron
       Preclinical and Phase I Human Studies of Hyperpolarized Carbon-13 MRI

17:30       Glass of wine offered by the City of Lausanne

18:30       Free evening



Saturday September 10, 2011

------        Biomedical applications II                                                                                    

8:30        Damian Tyler
        Investigating the Mechanisms of Cardiovascular Disease Using Hyperpolarized
        Magnetic Resonance
9:00        Steven Reynolds
        Improved Hyperpolarised 13C Pyruvate Metabolism Model Using Measured
        Arterial Input Function in a Rat Tumour Model
9:15        Matthew Merritt
        A Study of Metabolism in the Perfused Liver Using Hyperpolarized Pyruvate
9:45        Mor Mishkovsky
        Studying brain metabolism in vivo via hyperpolarized magnetic resonance

10:15       Coffee break

11:00       Malgorzata Marjanska
       Hyperpolarized 13C spectroscopy in rat brain
11:30       Rolf Schulte
       Advanced Parallel Imaging Techniques for Metabolic Imaging with
       Hyperpolarised 13C
11:45       Alexander Barnes
       DNP at 16.4 and 8.9 Tesla with TUnable Gyrotrons and High-Resolution Cryogenic
       MAS Probes

12:15       Closing remarks




Registration fee: 300 CHF

Registration


The abstract submission process is independent of the registration process
and you need to register even if you have submitted an abstract.

Submit abstract




Local organizing committee

Geoffrey Bodenhausen
Jean-Philippe Ansermet
Rolf Gruetter
Stefano Alberti
Arnaud Comment

and collaborators: S. Ulzega, M. Caporini, S. Jannin, V. Vitzthum, P. Miéville, A. Macor, E. De Rijk.















Contact: please write to DNPmeeting2011@epfl.ch